Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7815332 | 0.96 | SLC2A1 (0.50) | SLC2A1MEN1KMT2AMCHR1ALOX15 | |
| SCHEMBL7978299 | 0.74 | MCHR1 (0.62) | SLC2A1MEN1KMT2AMCHR1ALOX15 | |
| SCHEMBL7978307 | 0.74 | MCHR1 (0.62) | SLC2A1MEN1KMT2AMCHR1ALOX15 | |
| SCHEMBL7978296 | 0.74 | MCHR1 (0.62) | SLC2A1MEN1KMT2AMCHR1ALOX15 | |
| SCHEMBL6607915 | 0.72 | SLC2A1 (0.62) | SLC2A1MEN1KMT2AALOX15SMN1; SMN2 | |
| SCHEMBL7812693 | 0.71 | SLC2A1 (0.61) | SLC2A1ALOX15SMN1; SMN2LMNAHPGD | |
| Hydrochloric Acid SCHEMBL6607447 | 0.71 | SLC2A1 (0.61) | SLC2A1MEN1KMT2AALOX15SMN1; SMN2 | |
| SCHEMBL6605276 | 0.70 | SLC2A1 (0.54) | SLC2A1MEN1KMT2AMCHR1ALOX15 | |
| SCHEMBL6589693 | 0.70 | SLC2A1 (0.54) | SLC2A1MEN1KMT2AALOX15SMN1; SMN2 | |
| SCHEMBL7805481 | 0.70 | SLC2A1 (0.60) | SLC2A1SMN1; SMN2LMNAHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6320051-B1 | AMINO(NH) OR OXYGEN(O) SUBSTITUTED, ENZYME INHIBITORS OF STAPHLOCCOCUS AUREUS METHIONYL T-RNA SYNTHETASE (MRS); ANTIBACTERIAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 2001-11-20 | — | — | US | disclosed |
| EP-1084110-A1 | QUINOLONES USED AS MRS INHIBITORS AND BACTERICIDES | SMITHKLINE BEECHAM PLC (GB) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999055677-A1 | QUINOLONES USED AS MRS INHIBITORS AND BACTERICIDES | SMITHKLINE BEECHAM PLC (GB) | 1999-11-04 | — | — | WO | disclosed |