Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | ACHE | P22303 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.37 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30058349 | 1.00 | TSHR (0.50) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL2502467 | 1.00 | TSHR (0.50) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL29700602 | 1.00 | TSHR (0.50) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL199961 | 1.00 | TSHR (0.50) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL29464227 | 1.00 | TSHR (0.50) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL138533 | 1.00 | TSHR (0.50) | TSHRACHEALDH1A1CA1CA2 | |
| Hydrochloric Acid SCHEMBL290288 | 0.97 | TSHR (0.47) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL29357701 | 0.97 | TSHR (0.53) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL4480 | 0.97 | TSHR (0.53) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL3127305 | 0.97 | TSHR (0.53) | TSHRACHEALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1290275-A | Catalyst and process for polymerization of cycloolefin | GOODRICH CO B F (US) | 2001-04-04 | — | — | CN | claimed |
| EP-0977628-B1 | CARBONYLATION CATALYST SYSTEM | DSM NV (NL) | 2001-06-20 | — | — | EP | disclosed |
| US-6232262-B1 | PALLADIUM COMPOUND, AN ACID COMPOUND HAVING A PKA>2 MEASURED IN WATER OF 18 DEGREES C. AND AN NON-SYMMETRICAL BIDENTATE PHOSPHOROUS LIGAND | DSM N?V? (NL) | 2001-05-15 | — | — | US | disclosed |
| EP-0977628-A1 | CARBONYLATION CATALYST SYSTEM | DSM N.V. (NL) | 2000-02-09 | — | — | EP | disclosed |
| WO-1998045040-A1 | CARBONYLATION CATALYST SYSTEM | DSM N.V. (NL) | 1998-10-15 | — | — | WO | disclosed |