Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.72 |
| ▸ | SMG1 | Q96Q15 | 6/20 | 0.62 |
| ▸ | CDK1 | P06493 | 4/20 | 0.62 |
| ▸ | CDK2 | P24941 | 4/20 | 0.62 |
| ▸ | MTOR | P42345 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | CDK4 | P11802 | 1/20 | 0.62 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.62 |
| ▸ | XBP1 | P17861 | 1/20 | 0.62 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.62 |
| ▸ | CCND1 | P24385 | 1/20 | 0.62 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | CDK7 | P50613 | 1/20 | 0.62 |
| ▸ | CDK9 | P50750 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | CCNH | P51946 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6109026 | 0.96 | CSNK2A1 (0.69) | CSNK2A1SMG1CDK1CDK2MTOR | |
| SCHEMBL6107651 | 0.84 | CSNK2A1 (1.00) | CSNK2A1SMG1CDK1CDK2MTOR | |
| Monoethanolamine SCHEMBL7817266 | 0.81 | CSNK2A1 (0.85) | CSNK2A1SMG1CDK1CDK2MTOR | |
| SCHEMBL13698056 | 0.79 | KDR (0.59) | CSNK2A1SMG1CDK1CDK2MTOR | |
| SCHEMBL6094407 | 0.79 | CDK1 (0.88) | CSNK2A1SMG1CDK1CDK2MTOR | |
| SCHEMBL5733802 | 0.79 | CSNK2A1 (0.80) | CSNK2A1SMG1CDK1CDK2MTOR | |
| SCHEMBL7817083 | 0.79 | CDK1 (0.91) | CSNK2A1SMG1CDK1CDK2MTOR | |
| SCHEMBL7813759 | 0.78 | CDK1 (0.85) | CSNK2A1SMG1CDK1CDK2MTOR | |
| SCHEMBL6108097 | 0.78 | CSNK2A1 (0.69) | CSNK2A1SMG1CDK1CDK2MTOR | |
| SCHEMBL6107663 | 0.77 | SMG1 (1.00) | CSNK2A1SMG1CDK1CDK2MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672041-B1 | PHARMACOLOGICALLY ACTIVE PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | NOVARTIS AG (CH) | 2001-11-14 | — | — | EP | disclosed |