Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 4/20 | 0.52 |
| ▸ | PPARG | P37231 | 3/20 | 0.51 |
| ▸ | PPARA | Q07869 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7804408 | 0.91 | PPARA (0.53) | NAMPTPPARGPPARAALOX15ALDH1A1 | |
| SCHEMBL7811809 | 0.90 | NAMPT (0.57) | NAMPTPPARGPPARAALOX15ALDH1A1 | |
| SCHEMBL7804727 | 0.90 | PPARG (0.53) | NAMPTPPARGPPARAALOX15ALDH1A1 | |
| SCHEMBL7809900 | 0.89 | PPARA (0.49) | NAMPTPPARGPPARAHPGD | |
| SCHEMBL7817567 | 0.89 | PPARA (0.64) | NAMPTPPARGPPARAALDH1A1MAPT | |
| SCHEMBL7813924 | 0.89 | PPARA (0.51) | NAMPTPPARGPPARAALOX15MAPT | |
| SCHEMBL7813581 | 0.89 | PPARA (0.51) | NAMPTPPARGPPARAALOX15ALDH1A1 | |
| SCHEMBL7811760 | 0.89 | PPARG (0.49) | NAMPTPPARGPPARAALOX15NPC1 | |
| SCHEMBL7811694 | 0.88 | PPARG (0.52) | NAMPTPPARGPPARAALDH1A1SMN1; SMN2 | |
| SCHEMBL7817615 | 0.85 | PPARG (0.48) | NAMPTPPARGPPARAALOX15NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |