SCHEMBL7811494

SCHEMBL7811494

CCC(O)CSc1nsnc1C1CN2CCC1CC2

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.45
CHRM1 P11229 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxalic Acid SCHEMBL7818279 0.94 CHRM2 (0.44) CHRM2CHRM1
SCHEMBL7818388 0.85 CHRM2 (0.48) CHRM2
SCHEMBL7818981 0.83 CHRM2 (0.51) CHRM2CHRM1
SCHEMBL7818281 0.82 CHRM2 (0.41) CHRM2CHRM1
SCHEMBL7811117 0.81 CHRM2 (0.46) CHRM2CHRM1
SCHEMBL7811511 0.81 CHRM1 (0.62) CHRM1
SCHEMBL7819693 0.80 CHRM2 (0.44) CHRM2CHRM1
Oxalic Acid SCHEMBL7820145 0.79 CHRM2 (0.48) CHRM2CHRM1
Vedaclidine SCHEMBL995360 0.79 CHRM1 (0.63) CHRM1
SCHEMBL7819638 0.79 CHRM2 (0.47) CHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6281233-B1 AZABICYCLIC RING-SUBSTITUTED THIA- OR OXADIAZOLES NOVO NORDISK A/S (DK) 2001-08-28 US claimed
EP-0714394-B1 ANTIPSYCHOTIC METHOD WITH THIADIAZOLE AND OXADIAZOLE DERIVATIVES NOVO NORDISK AS (DK) 2001-06-20 EP claimed
EP-0873124-A1 A METHOD OF TREATING HYPERCHOLESTEROLEMIA AND RELATED DISORDERS NOVO NORDISK A/S (DK) 1998-10-28 EP claimed
EP-0790995-A1 A METHOD OF TREATING URINARY BLADDER DYSFUNCTIONS NOVO NORDISK A/S (DK) 1997-08-27 EP claimed
WO-1997025043-A1 A METHOD OF TREATING HYPERCHOLESTEROLEMIA AND RELATED DISORDERS NOVO NORDISK A/S (DK) 1997-07-17 WO claimed
EP-0735869-A1 A METHOD OF TREATING GASTROINTESTINAL MOTILITY DISORDERS NOVO NORDISK A/S (DK) 1996-10-09 EP claimed
EP-0714394-A1 ANTIPSYCHOTIC METHOD NOVO NORDISK A/S (DK) 1996-06-05 EP claimed
WO-1996014316-A1 A METHOD OF TREATING URINARY BLADDER DYSFUNCTIONS NOVO NORDISK A/S (DK) 1996-05-17 WO claimed
WO-1995017180-A1 A METHOD OF TREATING GASTROINTESTINAL MOTILITY DISORDERS NOVO NORDISK A/S (DK) 1995-06-29 WO claimed
WO-1995005379-A1 ANTIPSYCHOTIC METHOD NOVO NORDISK A/S (DK) 1995-02-23 WO claimed
EP-0873124-A1 A METHOD OF TREATING HYPERCHOLESTEROLEMIA AND RELATED DISORDERS NOVO NORDISK A/S (DK) 1998-10-28 EP disclosed
WO-1997025043-A1 A METHOD OF TREATING HYPERCHOLESTEROLEMIA AND RELATED DISORDERS NOVO NORDISK A/S (DK) 1997-07-17 WO disclosed