SCHEMBL781190

SCHEMBL781190

COP(=O)(C(=O)c1ccccc1C)C(=O)c1ccccc1C

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
HPGD P15428 3/20 0.46
LMNA P02545 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
POLB P06746 2/20 0.42
KMT2A Q03164 2/20 0.42
KCNK3 O14649 1/20 0.42
KCNK9 Q9NPC2 1/20 0.42
DHODH Q02127 1/20 0.41
ALDH1A1 P00352 4/20 0.41
KDM4E B2RXH2 2/20 0.41
HSD17B10 Q99714 1/20 0.41
TYK2 P29597 1/20 0.41
MAPT P10636 1/20 0.41
ALOX12 P18054 1/20 0.41
ERCC5 P28715 1/20 0.41
FEN1 P39748 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL776959 0.85 NPC1 (0.46) NPC1RAB9AHPGDLMNASMN1; SMN2
SCHEMBL777428 0.81 NPC1 (0.44) NPC1RAB9AHPGDLMNASMN1; SMN2
SCHEMBL778657 0.80 KMT2A (0.51) NPC1RAB9AHPGDLMNASMN1; SMN2
SCHEMBL443122 0.79 HPGD (0.52) NPC1RAB9AHPGDSMN1; SMN2POLB
SCHEMBL2258548 0.79 HPGD (0.52) NPC1RAB9AHPGDSMN1; SMN2POLB
SCHEMBL13811184 0.79 KMT2A (0.43) NPC1RAB9AHPGDLMNAKMT2A
SCHEMBL57794 0.79 NPC1 (0.45) NPC1RAB9AHPGDLMNASMN1; SMN2
SCHEMBL779190 0.78 HPGD (0.50) NPC1RAB9AHPGDSMN1; SMN2POLB
SCHEMBL1034215 0.74 HPGD (0.47) NPC1RAB9AHPGDSMN1; SMN2POLB
SCHEMBL779208 0.74 KMT2A (0.46) NPC1RAB9AHPGDLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9343777-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-05-17 US disclosed
US-9252457-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-02-02 US disclosed
US-20120177988-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-07-12 US disclosed
US-20120070731-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-03-22 US disclosed