Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 6/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7814776 | 0.99 | ACE (0.40) | ACEMMESRCAPPNPY1R | |
| SCHEMBL7814341 | 0.99 | ACE (0.40) | ACEMMESRCAPPNPY1R | |
| SCHEMBL5408640 | 0.85 | SRC (0.50) | ACEMMESRCAPPNPY1R | |
| SCHEMBL13929781 | 0.73 | APP (0.49) | ACEMMESRCAPPNPY1R | |
| SCHEMBL13929813 | 0.73 | APP (0.49) | ACEMMESRCAPPNPY1R | |
| SCHEMBL14169965 | 0.73 | GAA (0.39) | ACEMMEALOX5APFEN1 | |
| SCHEMBL10209107 | 0.71 | GAA (0.38) | ACEMMESRCAPPALOX5AP | |
| SCHEMBL7817778 | 0.71 | CYP2D6 (0.42) | — | |
| SCHEMBL21143944 | 0.71 | ACE (0.44) | ACEMMESRCAPPNPY1R | |
| SCHEMBL5638958 | 0.71 | ACE (0.44) | ACEMMESRCAPPNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0794184-B1 | 6-METHOXY-1H-BENZOTRIAZOLE-5-CARBOXAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO (JP) | 2001-05-30 | — | — | EP | disclosed |
| US-5932568-A | GASTROINTESTINAL DISORDERS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1999-08-03 | — | — | US | disclosed |
| EP-0794184-A1 | 6-METHOXY-1H-BENZOTRIAZOLE-5-CARBOXAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1997-09-10 | — | — | EP | disclosed |