Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 14/20 | 0.39 |
| ▸ | PPARG | P37231 | 13/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 10/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5854285 | 0.88 | PTPN1 (0.36) | PPARDPPARGFFAR1PPARAPTPN1 | |
| SCHEMBL5854607 | 0.88 | PTPN1 (0.36) | PPARDPPARGFFAR1PPARAPTPN1 | |
| SCHEMBL5854269 | 0.86 | PTPN1 (0.35) | PPARDPPARGFFAR1PTPN1HTR2B | |
| SCHEMBL5854582 | 0.86 | PPARG (0.34) | PPARDPPARGFFAR1PPARAPTPN1 | |
| SCHEMBL5854163 | 0.86 | PTPN1 (0.37) | PPARDPPARGFFAR1PPARAPTPN1 | |
| SCHEMBL5855214 | 0.85 | PTPN1 (0.35) | PPARDPPARGFFAR1PTPN1HTR2B | |
| SCHEMBL5853868 | 0.85 | PTPN1 (0.34) | PPARDPPARGFFAR1PTPN1HTR2B | |
| SCHEMBL5856178 | 0.84 | HTR2B (0.38) | PPARDPPARGFFAR1PPARAPTPN1 | |
| SCHEMBL5854218 | 0.84 | PTPN1 (0.33) | PPARDPPARGFFAR1PTPN1HTR2B | |
| SCHEMBL6788841 | 0.84 | PPARG (0.34) | PPARDPPARGFFAR1PPARAPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087959-A1 | NOVEL BENZOPYRAN OR THIOBENZOPYRAN DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999065893-A1 | NOVEL BENZOPYRAN OR THIOBENZOPYRAN DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 1999-12-23 | — | — | WO | disclosed |