Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 16/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL896997 | 0.88 | ALK (0.53) | ALK | |
| SCHEMBL7809417 | 0.86 | ALK (0.41) | ALK | |
| SCHEMBL896895 | 0.85 | ALK (0.62) | ALK | |
| SCHEMBL1755908 | 0.83 | ALK (0.50) | ALKMAPTALDH1A1 | |
| SCHEMBL7809425 | 0.76 | ALK (0.59) | ALK | |
| SCHEMBL7811873 | 0.75 | ALK (0.72) | ALK | |
| SCHEMBL7810970 | 0.74 | ALK (0.55) | ALK | |
| SCHEMBL1755809 | 0.74 | ALK (0.54) | ALK | |
| SCHEMBL7811871 | 0.74 | ALK (0.57) | ALK | |
| SCHEMBL1755955 | 0.72 | ALK (0.52) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010143664-A1 | TETRACYCLIC COMPOUND | 中外製薬株式会社 (JP) | 2010-12-16 | — | — | WO | disclosed |