Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7824827 | 0.78 | SLC6A2 (0.58) | HRH3MAPTALDH1A1KDM4ELMNA | |
| SCHEMBL13272386 | 0.75 | ATM (0.50) | ATMALDH1A1DRD2HTR2AHRH1 | |
| SCHEMBL23022739 | 0.74 | ATM (0.51) | ATMALDH1A1DRD2HTR2AHRH1 | |
| SCHEMBL3303532 | 0.74 | HRH3 (0.52) | HRH3MAPTALDH1A1KDM4ELMNA | |
| SCHEMBL3301450 | 0.74 | BPTF (0.54) | HRH3MAPTALDH1A1KDM4ELMNA | |
| SCHEMBL17856803 | 0.74 | CYP2A13 (0.50) | ATMDRD2HTR2AHRH1KMT2A | |
| Hydrochloric Acid SCHEMBL7403695 | 0.73 | TMEM97 (0.57) | ATMDRD2HTR2AHRH1 | |
| SCHEMBL20502324 | 0.73 | CYP2C9 (0.53) | ATMDRD2HTR2AHRH1KMT2A | |
| SCHEMBL22532645 | 0.73 | KDM4E (0.53) | HRH3MAPTALDH1A1KDM4EGRIN1 | |
| SCHEMBL22532691 | 0.73 | HRH3 (0.52) | HRH3MAPTALDH1A1KDM4EGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140834-A1 | HETEROCYCLIC PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Du Pont Pharmaceuticals Company (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035877-A1 | HETEROCYCLIC PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-06-22 | — | — | WO | disclosed |