Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.64 |
| ▸ | KDR | P35968 | 5/20 | 0.64 |
| ▸ | KIT | P10721 | 3/20 | 0.64 |
| ▸ | INSR | P06213 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7819599 | 0.92 | ALK (0.64) | ALKKDRKITINSR | |
| SCHEMBL7802993 | 0.91 | ALK (0.78) | ALKKDRKITINSR | |
| SCHEMBL7800558 | 0.91 | ALK (0.63) | ALKKDRKIT | |
| SCHEMBL7816383 | 0.90 | ALK (0.78) | ALKKDRKITINSR | |
| SCHEMBL7819778 | 0.89 | ALK (0.78) | ALKKDRKITINSR | |
| SCHEMBL7809334 | 0.88 | ALK (0.79) | ALKKDRKIT | |
| SCHEMBL7800597 | 0.88 | ALK (0.80) | ALKKDRKITINSR | |
| SCHEMBL896954 | 0.88 | ALK (0.84) | ALKKDRKITINSR | |
| SCHEMBL7812954 | 0.88 | ALK (0.69) | ALKKDRKITINSR | |
| SCHEMBL7803718 | 0.88 | ALK (0.65) | ALKKDRKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010143664-A1 | TETRACYCLIC COMPOUND | 中外製薬株式会社 (JP) | 2010-12-16 | — | — | WO | disclosed |