Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5928724 | 0.80 | TSHR (0.68) | TSHRTDP1KMT2AGAAKDM4E | |
| SCHEMBL3860229 | 0.78 | TSHR (0.66) | TSHRTDP1KMT2AGAAKDM4E | |
| SCHEMBL12811737 | 0.77 | KMT2A (0.71) | TSHRTDP1KMT2AGAAKDM4E | |
| SCHEMBL25904137 | 0.77 | TSHR (0.65) | TSHRTDP1KMT2AGAAKDM4E | |
| SCHEMBL448609 | 0.77 | TSHR (0.65) | TSHRTDP1KMT2AGAAKDM4E | |
| SCHEMBL6715728 | 0.77 | TSHR (0.60) | TSHRTDP1KMT2AGAAKDM4E | |
| SCHEMBL28304178 | 0.77 | TSHR (0.60) | TSHRTDP1KMT2AGAAKDM4E | |
| SCHEMBL10362634 | 0.76 | TSHR (0.56) | TSHRTDP1KMT2AGAAKDM4E | |
| SCHEMBL13936399 | 0.76 | KMT2A (0.73) | TSHRTDP1KMT2AGAAKDM4E | |
| SCHEMBL17115785 | 0.75 | TSHR (0.63) | TSHRTDP1KMT2AGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |