Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12835323 | 0.88 | HSD17B10 (0.55) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL12835264 | 0.86 | CYP1A2 (0.54) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL12172978 | 0.86 | HSD17B10 (0.54) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL7819848 | 0.86 | NPC1 (0.62) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL12835335 | 0.83 | KDR (0.62) | RAB9AMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL11282689 | 0.83 | CYP1A2 (0.51) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL11258906 | 0.83 | CYP1A2 (0.51) | MEN1KMT2AMAPTCYP1A2CYP3A4 | |
| SCHEMBL7824986 | 0.81 | CYP1A2 (0.55) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL7820662 | 0.81 | CYP1A2 (0.56) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL19033863 | 0.80 | NPC1 (0.55) | NPC1RAB9AMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |