Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 8/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL859404 | 0.91 | PIK3CA (0.37) | PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL8531105 | 0.90 | PIK3CA (0.36) | PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL861994 | 0.88 | PIK3CA (0.37) | PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL855923 | 0.88 | PIK3CA (0.35) | PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL3763058 | 0.88 | PIK3CA (0.36) | PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL856970 | 0.86 | PIK3CA (0.34) | PIK3CAPIK3CDPIK3CB | |
| SCHEMBL855942 | 0.86 | PIK3CA (0.34) | PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL856864 | 0.85 | PIK3CA (0.35) | PIK3CA | |
| SCHEMBL15523011 | 0.85 | PIK3CA (0.33) | PIK3CA | |
| SCHEMBL862092 | 0.85 | PIK3CA (0.35) | PIK3CAPIK3CDPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010135568-A1 | BENZOXAZEPINES AS INHIBITORS OF MTOR AND THEIR USE TO TREAT CANCER | EXELIXIS, INC. (US) | 2010-11-25 | — | — | WO | disclosed |