Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5164310 | 0.91 | BACE1 (0.54) | BACE1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL5991804 | 0.90 | MEN1 (0.51) | BACE1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL5163093 | 0.89 | BACE1 (0.52) | BACE1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL5351103 | 0.89 | BACE1 (0.52) | BACE1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL8191231 | 0.87 | BACE1 (0.45) | BACE1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL8191227 | 0.87 | BACE1 (0.45) | BACE1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL8191233 | 0.87 | BACE1 (0.45) | BACE1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL29901207 | 0.85 | BACE1 (0.53) | BACE1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL14191577 | 0.85 | BACE1 (0.53) | BACE1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL6598985 | 0.83 | TSHR (0.49) | BACE1MAPTMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |