Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CCR3 | P51677 | 8/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7822361 | 1.00 | MEN1 (0.47) | MEN1KMT2APOLBCCR3 | |
| SCHEMBL7825545 | 0.83 | CCR3 (0.56) | CCR3 | |
| SCHEMBL7829231 | 0.83 | CCR3 (0.56) | CCR3 | |
| SCHEMBL7822342 | 0.83 | CCR3 (0.54) | MEN1KMT2ACCR3 | |
| SCHEMBL7824966 | 0.83 | CCR3 (0.54) | MEN1KMT2ACCR3 | |
| SCHEMBL7822339 | 0.83 | CCR3 (0.54) | MEN1KMT2ACCR3 | |
| SCHEMBL5352298 | 0.79 | CCR3 (0.56) | MEN1KMT2APOLBCCR3 | |
| SCHEMBL7820582 | 0.78 | CCR3 (0.50) | CCR3 | |
| SCHEMBL7820579 | 0.78 | CCR3 (0.50) | CCR3 | |
| SCHEMBL7813662 | 0.78 | CCR3 (0.50) | CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140834-A1 | HETEROCYCLIC PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Du Pont Pharmaceuticals Company (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035877-A1 | HETEROCYCLIC PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-06-22 | — | — | WO | disclosed |