Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | GAA | P10253 | 4/20 | 0.67 |
| ▸ | PPM1B | O75688 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19425502 | 0.86 | POLB (0.75) | POLBMEN1KMT2AALDH1A1GAA | |
| SCHEMBL5862372 | 0.86 | POLB (0.75) | POLBMEN1KMT2AALDH1A1GAA | |
| SCHEMBL20705655 | 0.86 | POLB (0.75) | POLBMEN1KMT2AALDH1A1GAA | |
| SCHEMBL728496 | 0.85 | POLB (0.74) | POLBMEN1KMT2AALDH1A1GAA | |
| SCHEMBL15702626 | 0.85 | POLB (0.78) | POLBMEN1KMT2AALDH1A1GAA | |
| SCHEMBL7822057 | 0.85 | POLB (0.74) | POLBMEN1KMT2AALDH1A1GAA | |
| SCHEMBL19425598 | 0.85 | POLB (0.74) | POLBMEN1KMT2AALDH1A1GAA | |
| SCHEMBL20009934 | 0.85 | POLB (1.00) | POLBMEN1KMT2AALDH1A1GAA | |
| SCHEMBL15702588 | 0.85 | POLB (0.74) | POLBMEN1KMT2AALDH1A1GAA | |
| SCHEMBL726935 | 0.85 | POLB (0.74) | POLBMEN1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |