Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PEPD | P12955 | 1/20 | 0.50 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.46 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7818915 | 1.00 | EPHX1 (0.56) | EPHX1ALDH1A1LMNAPEPDGRM4 | |
| SCHEMBL1258973 | 1.00 | EPHX1 (0.56) | EPHX1ALDH1A1LMNAPEPDGRM4 | |
| SCHEMBL7818913 | 1.00 | EPHX1 (0.56) | EPHX1ALDH1A1LMNAPEPDGRM4 | |
| SCHEMBL7815469 | 1.00 | EPHX1 (0.56) | EPHX1ALDH1A1LMNAPEPDGRM4 | |
| SCHEMBL26551907 | 1.00 | EPHX1 (0.56) | EPHX1ALDH1A1LMNAPEPDGRM4 | |
| SCHEMBL28500197 | 0.97 | EPHX1 (0.54) | EPHX1ALDH1A1LMNAPEPDGRM4 | |
| SCHEMBL8411456 | 0.95 | PEPD (0.56) | EPHX1ALDH1A1LMNAPEPDGRM4 | |
| SCHEMBL7761680 | 0.95 | PEPD (0.56) | EPHX1ALDH1A1LMNAPEPDGRM4 | |
| SCHEMBL8411453 | 0.95 | PEPD (0.56) | EPHX1ALDH1A1LMNAPEPDGRM4 | |
| SCHEMBL7761683 | 0.95 | PEPD (0.56) | EPHX1ALDH1A1LMNAPEPDGRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798298-B1 | THIAZOLIDINONE OR OXAZOLIDINONE DERIVATIVES TO TREAT ANGINA PECTORIS OR COMPOSITIONS CONTAINING THE SAME AS ACTIVE INGREDIENT | SANKYO CO (JP) | 2001-08-08 | — | — | EP | disclosed |
| JP-2000128840-A | PRODUCTION OF CIS-2-AMINOCYCLOHEXANECARBOXYLIC ACID AND CIS-2-BENZAMIDECYCLOHEXANECARBOXYLIC ACID | YAMAKAWA YAKUHIN KOGYO KK | 2000-05-09 | — | — | JP | disclosed |
| US-5843973-A | Thiazolidinone compounds and composition for angina pectoris comprising the compounds as an active ingredient | SANKYO COMPANY, LIMITED (JP) | 1998-12-01 | — | — | US | disclosed |
| EP-0798298-A1 | THIAZOLIDINONE COMPOUNDS OR ANGINA PECTORIS REMEDY OR PREVENTIVE CONTAINING THE SAME AS ACTIVE INGREDIENT | SANKYO COMPANY LIMITED (JP) | 1997-10-01 | — | — | EP | disclosed |