Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | ACACB | O00763 | 9/20 | 0.49 |
| ▸ | ACACA | Q13085 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | CKS1B | P61024 | 1/20 | 0.43 |
| ▸ | SKP1 | P63208 | 1/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3945277 | 1.00 | KMT2A (0.51) | KMT2ADRD2ACACBACACATDP1 | |
| SCHEMBL1491414 | 1.00 | KMT2A (0.51) | KMT2ADRD2ACACBACACATDP1 | |
| SCHEMBL3942686 | 0.93 | KMT2A (0.56) | KMT2ADRD2ACACBACACATDP1 | |
| SCHEMBL4377073 | 0.93 | KMT2A (0.56) | KMT2ADRD2ACACBACACATDP1 | |
| SCHEMBL190838 | 0.93 | KMT2A (0.56) | KMT2ADRD2ACACBACACATDP1 | |
| SCHEMBL3816616 | 0.93 | KMT2A (0.56) | KMT2ADRD2ACACBACACATDP1 | |
| Formaldehyde SCHEMBL28082239 | 0.89 | KMT2A (0.54) | KMT2ADRD2ACACBACACATDP1 | |
| Bicarbonate SCHEMBL1580718 | 0.89 | KMT2A (0.57) | KMT2ADRD2ACACBACACAEPHX1 | |
| SCHEMBL7817062 | 0.88 | ACACB (0.51) | KMT2ADRD2ACACBACACATDP1 | |
| SCHEMBL7817058 | 0.88 | ACACB (0.51) | KMT2ADRD2ACACBACACATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019063748-A1 | ROR-GAMMA INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-04-04 | — | — | WO | disclosed |
| EP-0798298-B1 | THIAZOLIDINONE OR OXAZOLIDINONE DERIVATIVES TO TREAT ANGINA PECTORIS OR COMPOSITIONS CONTAINING THE SAME AS ACTIVE INGREDIENT | SANKYO CO (JP) | 2001-08-08 | — | — | EP | disclosed |
| US-5843973-A | Thiazolidinone compounds and composition for angina pectoris comprising the compounds as an active ingredient | SANKYO COMPANY, LIMITED (JP) | 1998-12-01 | — | — | US | disclosed |
| EP-0798298-A1 | THIAZOLIDINONE COMPOUNDS OR ANGINA PECTORIS REMEDY OR PREVENTIVE CONTAINING THE SAME AS ACTIVE INGREDIENT | SANKYO COMPANY LIMITED (JP) | 1997-10-01 | — | — | EP | disclosed |