Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 2/20 | 0.75 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.56 |
| ▸ | DRD2 | P14416 | 3/20 | 0.56 |
| ▸ | HTR7 | P34969 | 3/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8200961 | 0.99 | HTR2B (0.77) | HTR2BCHRM4DRD2HTR7HTR2A | |
| SCHEMBL8659369 | 0.93 | HTR2B (0.83) | HTR2BCHRM4DRD2HTR7HTR2A | |
| Hydrochloric Acid SCHEMBL7817705 | 0.92 | HTR2B (0.85) | HTR2BCHRM4DRD2HTR7HTR2A | |
| SCHEMBL7817554 | 0.89 | HTR2B (0.77) | HTR2BCHRM4DRD2HTR7HTR2A | |
| SCHEMBL11043054 | 0.87 | HTR2B (0.98) | HTR2BCHRM4DRD2HTR7HTR2A | |
| SCHEMBL29462336 | 0.87 | HTR2B (0.98) | HTR2BCHRM4DRD2HTR7HTR2A | |
| SCHEMBL9391684 | 0.87 | HTR2B (0.98) | HTR2BCHRM4DRD2HTR7HTR2A | |
| Hydrochloric Acid SCHEMBL29727825 | 0.86 | HTR2B (1.00) | HTR2BCHRM4DRD2HTR7HTR2A | |
| Hydrochloric Acid SCHEMBL7828661 | 0.86 | HTR2B (1.00) | HTR2BCHRM4DRD2HTR7HTR2A | |
| SCHEMBL7819788 | 0.85 | HTR2B (0.70) | HTR2BCHRM4DRD2HTR7HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749313-A4 | METHOD FOR TREATING 5HT 2B RECEPTOR RELATED CONDITIONS | LILLY CO ELI (US) | 2001-10-24 | — | — | EP | disclosed |
| EP-0749313-A1 | METHOD FOR TREATING 5HT 2B RECEPTOR RELATED CONDITIONS | ELI LILLY AND COMPANY (US) | 1996-12-27 | — | — | EP | disclosed |
| WO-1995024200-A1 | METHOD FOR TREATING 5HT2B RECEPTOR RELATED CONDITIONS | ELI LILLY AND COMPANY (US) | 1995-09-14 | — | — | WO | disclosed |
| WO-1994023720-A1 | TETRAHYDRO-BETA-CARBOLINES | ELI LILLY AND COMPANY (US) | 1994-10-27 | — | — | WO | disclosed |