⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11300588 | 0.81 | MAPT (0.31) | — | |
| SCHEMBL30612950 | 0.62 | — | — | |
| SCHEMBL30612952 | 0.62 | — | — | |
| SCHEMBL9165798 | 0.60 | — | — | |
| SCHEMBL10510804 | 0.60 | — | — | |
| SCHEMBL8906209 | 0.60 | — | — | |
| SCHEMBL6215518 | 0.59 | — | — | |
| SCHEMBL9354627 | 0.58 | — | — | |
| SCHEMBL4956 | 0.57 | — | — | |
| SCHEMBL3065946 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717042-B1 | Process for preparing 1-(4,5-Dihydro-2-thiazolyle)-3-azetidine thiol derivatives | WYETH LEDERLE JAPAN LTD (JP) | 2001-05-23 | — | — | EP | disclosed |
| US-5783703-A | CARBAPENEM INTERMEDIATES | LEDERLE (JAPAN), LTD. (JP) | 1998-07-21 | — | — | US | disclosed |
| US-5659043-A | BACTERICIDES | LEDERLE (JAPAN) LTD. (JP) | 1997-08-19 | — | — | US | disclosed |
| EP-0717042-A1 | 1-(4,5-Dihydro-2-thiazolyle)-3-azetidine thiol derivatives | LEDERLE (JAPAN), Ltd. (JP) | 1996-06-19 | — | — | EP | disclosed |