Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 6/20 | 0.71 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.71 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.71 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.71 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.71 |
| ▸ | PTGFR | P43088 | 2/20 | 0.71 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.52 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.50 |
| ▸ | PTGIR | P43119 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7817228 | 1.00 | PTGER3 (0.71) | PTGER3PTGDRPTGER4PTGER2TBXA2R | |
| SCHEMBL7922115 | 0.83 | PTGER3 (1.00) | PTGER3PTGDRPTGER4PTGER2TBXA2R | |
| SCHEMBL7922112 | 0.83 | PTGER3 (1.00) | PTGER3PTGDRPTGER4PTGER2TBXA2R | |
| SCHEMBL7819867 | 0.83 | PTGER3 (0.74) | PTGER3PTGDRPTGER4PTGER2TBXA2R | |
| SCHEMBL7819865 | 0.83 | PTGER3 (0.74) | PTGER3PTGDRPTGER4PTGER2TBXA2R | |
| SCHEMBL7929714 | 0.76 | PTGER3 (1.00) | PTGER3PTGDRPTGER4PTGER2TBXA2R | |
| SCHEMBL7929719 | 0.76 | PTGER3 (1.00) | PTGER3PTGDRPTGER4PTGER2TBXA2R | |
| SCHEMBL7929782 | 0.76 | PTGER3 (0.64) | PTGER3PTGDRPTGER4PTGER2TBXA2R | |
| SCHEMBL7929784 | 0.76 | PTGER3 (0.64) | PTGER3PTGDRPTGER4PTGER2TBXA2R | |
| SCHEMBL2981091 | 0.75 | PTGER3 (0.70) | PTGER3PTGDRPTGER4PTGER2TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242493-B1 | PROSTAGLANDIN INHIBITORS; ANALGESICS, ANTIPYRETICS, ANTIINFLAMMATORY AGENTS | MERCK FROSST CANADA & CO. (CA) | 2001-06-05 | — | — | US | disclosed |
| EP-1071648-A2 | CARBOXYLIC ACIDS AND ACYLSULFONAMIDES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | Merck Frosst Canada & Co. (CA) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999047497-A2 | CARBOXYLIC ACIDS AND ACYLSULFONAMIDES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | MERCK FROSST CANADA & CO. (CA) | 1999-09-23 | — | — | WO | disclosed |