Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 5/20 | 0.51 |
| ▸ | GPR142 | Q7Z601 | 9/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3802603 | 0.90 | CREBBP (0.54) | CREBBPGPR142PIK3CAMTOR | |
| SCHEMBL856548 | 0.86 | CREBBP (0.59) | CREBBPGPR142PIK3CAMTOR | |
| SCHEMBL13056560 | 0.86 | CREBBP (0.52) | CREBBPGPR142PIK3CAMTORGBA1 | |
| SCHEMBL859534 | 0.84 | CREBBP (0.52) | CREBBPGPR142PIK3CAMTOR | |
| SCHEMBL857156 | 0.83 | CREBBP (0.51) | CREBBPGPR142PIK3CAMTORGBA1 | |
| SCHEMBL856266 | 0.83 | CREBBP (0.51) | CREBBPGPR142PIK3CAMTOR | |
| SCHEMBL858502 | 0.83 | CREBBP (0.50) | CREBBPGPR142PIK3CAMTORGBA1 | |
| SCHEMBL856776 | 0.81 | CREBBP (0.48) | CREBBPGPR142PIK3CAMTORGBA1 | |
| SCHEMBL3768497 | 0.80 | CREBBP (0.47) | CREBBPGPR142PIK3CAMTORGBA1 | |
| SCHEMBL857215 | 0.80 | CREBBP (0.51) | CREBBPGPR142PIK3CAMTORGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010135568-A1 | BENZOXAZEPINES AS INHIBITORS OF MTOR AND THEIR USE TO TREAT CANCER | EXELIXIS, INC. (US) | 2010-11-25 | — | — | WO | disclosed |