Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3GNRHRMPLPDE3APDE3BPDE4APDE4BPDE4CPDE4DPPARASLC5A2
The experimentally established mechanism targets of Choline. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Choline SCHEMBL8516093 | 0.96 | CYP3A4 (0.93) | — | |
| Choline SCHEMBL1934626 | 0.96 | MEN1 (0.80) | — | |
| Choline SCHEMBL29394392 | 0.96 | — | — | |
| Choline SCHEMBL16558587 | 0.96 | — | — | |
| Choline SCHEMBL27261423 | 0.96 | — | — | |
| Choline SCHEMBL8012313 | 0.96 | MEN1 (0.92) | — | |
| Choline SCHEMBL300867 | 0.96 | MEN1 (0.92) | — | |
| Choline SCHEMBL17629823 | 0.96 | MEN1 (0.92) | — | |
| Choline SCHEMBL14330721 | 0.96 | — | — | |
| Choline SCHEMBL13169639 | 0.96 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2666773-B1 | ORGANIC AMINE SALTS OF AZILSARTAN, PREPARATION METHOD AND USE THEREOF | JIANGSU HANSOH PHARMACEUTICAL CO LTD (CN) | 2017-07-26 | — | — | EP | claimed |
| CN-105503848-A | Azilsartan organic amine salt compound and preparation method and use thereof | JIANGSU HANSOH PHARMA GROUP CO LTD | 2016-04-20 | — | — | CN | claimed |
| US-9233954-B2 | Organic amine salts of Azilsartan, preparation method and use thereof | JIANGSU HANSOH PHARMACEUTICAL CO., LTD. (CN) | 2016-01-12 | — | — | US | claimed |
| CN-102603723-B | Azilsartan organic amine salts, and preparation method and application thereof | JIANGSU HANSOH MEDICAL GROUP CO.,LTD. (CN) | 2014-10-08 | — | — | CN | claimed |
| EP-2666773-A1 | ORGANIC AMINE SALTS OF AZILSARTAN, PREPARATION METHOD AND USE THEREOF | Jiangsu Hansoh Pharmaceutical Co., Ltd. (CN) | 2013-11-27 | — | — | EP | claimed |
| US-20130296334-A1 | ORGANIC AMINE SALTS OF AZILSARTAN, PREPARATION METHOD AND USE THEREOF | JIANGSU HANSOH PHARMACEUTICAL CO., LTD. (CN) | 2013-11-07 | — | — | US | claimed |
| CN-102603723-A | Azilsartan organic amine salts, and preparation method and application thereof | JIANGSU HANSOH PHARMACEUTICAL GROUP CO LTD | 2012-07-25 | — | — | CN | claimed |
| WO-2025242816-A1 | PROCESS FOR PREPARING 2,5-DIFORMYLFURAN | ANNIKKI GMBH (AT) | 2025-11-27 | — | — | WO | disclosed |
| WO-2024160906-A1 | ENZYMATIC PROCESS FOR THE PRODUCTION OF ALDARIC ACIDS | COÖPERATIE KONINKLIJKE COSUN U.A. (NL) | 2024-08-08 | — | — | WO | disclosed |
| US-11761017-B2 | Rice thermo-sensitive male sterile gene mutant tms18 and uses thereof | SHANGHAI NORMAL UNIVERSITY (CN) | 2023-09-19 | — | — | US | disclosed |
| WO-2023286634-A1 | LAYERED PRODUCT | 帝人株式会社 | 2023-01-19 | — | — | WO | disclosed |
| US-20220119836-A1 | Rice thermo-sensitive male sterile gene mutant tms18 and uses thereof | SHANGHAI NORMAL UNIVERSITY (CN) | 2022-04-21 | — | — | US | disclosed |
| US-10385238-B2 | Adhesive laminate | TEIJIN LIMITED (JP) | 2019-08-20 | — | — | US | disclosed |
| CN-1564742-A | Acrylic resin composition, organosiloxane resin composition and laminate comprising the same | TEIJIN CHEMICALS LTD (JP) | 2005-01-12 | — | — | CN | disclosed |
| US-20040247878-A1 | Acrylic resin composition organosiloxane resin composition and laminate comprising the same | TEIJIN CHEMICALS LTD. (JP) | 2004-12-09 | — | — | US | disclosed |
| CN-1511167-A | Low-molecular and high-molecular emulsifiers, in particular based on polyisobutene, and mixtures thereof | �����ɷ� | 2004-07-07 | — | — | CN | disclosed |
| CN-1455779-A | Clycerophosphoinositol derivatives as modulators of cytosolic phospholipase | I R B INST TO DI RICECHE BIOTE (IT) | 2003-11-12 | — | — | CN | disclosed |
| US-5871558-A | SUBJECTING A PARTIAL POLYCONDENSATION PRODUCT OF ALKOXYSILANE TO HYDROLYSIS IN THE PRESENCE OF A SOLVENT, AN ORGANIC POLYMERIC COMPOUND AND A BASIC CATALYST TO FORM A SOL, MAKING THE SOL INTO A GEL, DRYING THE GEL TO FORM A DRY GEL, AND | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1999-02-16 | — | — | US | disclosed |
| US-5225229-A | Aluminum hydroxide production | ALUMINUM COMPANY OF AMERICA (US) | 1993-07-06 | — | — | US | disclosed |
| US-4755374-A | Reacting water with aluminum in presence of choline | ALUMINUM COMPANY OF AMERICA (US) | 1988-07-05 | — | — | US | disclosed |