Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.63 |
| ▸ | KDR | P35968 | 4/20 | 0.58 |
| ▸ | KIT | P10721 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7805824 | 0.91 | ALK (0.75) | ALKKDRKIT | |
| SCHEMBL7805890 | 0.90 | ALK (0.61) | ALKKDRKIT | |
| SCHEMBL10272278 | 0.88 | ALK (0.65) | ALKKDRKIT | |
| SCHEMBL7806236 | 0.86 | ALK (0.63) | ALKKDRKIT | |
| SCHEMBL897186 | 0.86 | ALK (0.84) | ALKKDRKIT | |
| SCHEMBL7801277 | 0.84 | ALK (0.74) | ALKKDRKIT | |
| SCHEMBL1755866 | 0.83 | ALK (0.65) | ALKKDRKIT | |
| SCHEMBL7806740 | 0.83 | ALK (0.76) | ALKKDRKIT | |
| SCHEMBL7810830 | 0.82 | ALK (0.71) | ALKKDR | |
| SCHEMBL21443259 | 0.82 | ALK (0.72) | ALKKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010143664-A1 | TETRACYCLIC COMPOUND | 中外製薬株式会社 (JP) | 2010-12-16 | — | — | WO | disclosed |