Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 6/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 8/20 | 0.45 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | CLK2 | P49760 | 1/20 | 0.44 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.44 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.44 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.44 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6581325 | 0.91 | PARP1 (0.53) | PARP1AURKBAURKAHPSEDGAT1 | |
| SCHEMBL6584369 | 0.88 | PARP1 (0.50) | PARP1AURKBAURKAHPSEDGAT1 | |
| SCHEMBL7417491 | 0.83 | NPY5R (0.45) | PARP1PARP2 | |
| SCHEMBL7819660 | 0.83 | AURKB (0.71) | PARP1AURKBAURKAHPSEPRKD3 | |
| SCHEMBL3576975 | 0.82 | PARP1 (0.72) | PARP1AURKBAURKAPARP2 | |
| SCHEMBL6581301 | 0.81 | AURKB (0.47) | PARP1AURKBAURKAHPSEPRKD3 | |
| SCHEMBL7762915 | 0.81 | MGAM (0.55) | PARP1AURKBAURKAHPSEPARP2 | |
| SCHEMBL6581295 | 0.80 | AURKB (0.56) | PARP1AURKBAURKAHPSEPARP2 | |
| SCHEMBL3579915 | 0.78 | PARP1 (0.67) | PARP1AURKBAURKAPARP2 | |
| SCHEMBL6580718 | 0.77 | AURKB (0.61) | PARP1AURKBAURKAHPSEPRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1127052-A1 | SUBSTITUTED 2-PHENYLBENZIMIDAZOLES, THE PRODUCTION THEREOF AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 2001-08-29 | — | — | EP | disclosed |
| WO-2000026192-A1 | SUBSTITUTED 2-PHENYLBENZIMIDAZOLES, THE PRODUCTION THEREOF AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-11 | — | — | WO | disclosed |