SCHEMBL7820183

SCHEMBL7820183

CC(C)Oc1ccc(N(C)S(C)(=O)=O)cc1CNC1CCCNC1c1ccccc1

nearest known ligand 0.82

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 19/20 0.82
CYP2D6 P10635 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7820180 1.00 TACR1 (0.82) TACR1CYP2D6
SCHEMBL7820056 1.00 TACR1 (0.82) TACR1CYP2D6
Hydrochloric Acid SCHEMBL7824423 0.99 TACR1 (0.81) TACR1CYP2D6
Hydrochloric Acid SCHEMBL7824429 0.99 TACR1 (0.81) TACR1CYP2D6
Hydrochloric Acid SCHEMBL7824427 0.99 TACR1 (0.81) TACR1CYP2D6
SCHEMBL7818163 0.91 TACR1 (0.69) TACR1CYP2D6
SCHEMBL7812094 0.91 TACR1 (0.69) TACR1CYP2D6
SCHEMBL7818159 0.91 TACR1 (0.69) TACR1CYP2D6
Hydrochloric Acid SCHEMBL7812003 0.91 TACR1 (0.68) TACR1CYP2D6
Hydrochloric Acid SCHEMBL7812007 0.91 TACR1 (0.68) TACR1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0655996-B1 SUBSTITUTED BENZYLAMINO NITROGEN CONTAINING NON-AROMATIC HETEROCYCLES PFIZER (US) 2001-11-07 EP claimed
EP-1114823-A2 Substituted benzylamino nitrogen containing non-aromatic heterocycles PFIZER INC. (US) 2001-07-11 EP claimed
EP-0655996-A1 SUBSTITUTED BENZYLAMINO NITROGEN CONTAINING NON-AROMATIC HETEROCYCLES PFIZER INC. (US) 1995-06-07 EP claimed
WO-1994004496-A9 SUBSTITUTED BENZYLAMINO NITROGEN CONTAINING NON-AROMATIC HETEROCYCLES 1995-01-26 WO claimed
WO-1994004496-A1 SUBSTITUTED BENZYLAMINO NITROGEN CONTAINING NON-AROMATIC HETEROCYCLES PFIZER INC. (US) 1994-03-03 WO claimed