Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | APEX1 | P27695 | 2/20 | 0.60 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8999902 | 0.91 | APEX1 (0.70) | POLBAPEX1CTDSP1L3MBTL1ALDH1A1 | |
| SCHEMBL65212 | 0.89 | APEX1 (0.67) | POLBAPEX1CTDSP1L3MBTL1ALDH1A1 | |
| SCHEMBL1397921 | 0.89 | APEX1 (0.67) | POLBAPEX1CTDSP1L3MBTL1ALDH1A1 | |
| SCHEMBL29364883 | 0.89 | APEX1 (0.67) | POLBAPEX1CTDSP1L3MBTL1ALDH1A1 | |
| SCHEMBL29394064 | 0.89 | APEX1 (0.67) | POLBAPEX1CTDSP1L3MBTL1ALDH1A1 | |
| SCHEMBL268999 | 0.87 | APEX1 (0.65) | POLBAPEX1CTDSP1L3MBTL1ALDH1A1 | |
| SCHEMBL10450423 | 0.85 | APEX1 (0.64) | POLBAPEX1CTDSP1L3MBTL1ALDH1A1 | |
| SCHEMBL5426543 | 0.85 | APEX1 (0.64) | POLBAPEX1CTDSP1L3MBTL1ALDH1A1 | |
| SCHEMBL29435082 | 0.85 | APEX1 (0.64) | POLBAPEX1CTDSP1L3MBTL1ALDH1A1 | |
| SCHEMBL1296081 | 0.85 | APEX1 (0.64) | POLBAPEX1CTDSP1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
| US-5530130-A | DYEING PLASTICS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |
| EP-0639624-A1 | Phthaloperinone dyestuffs | BAYER AG (DE) | 1995-02-22 | — | — | EP | disclosed |