Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7832666 | 0.86 | CYP4F2 (0.46) | MAPTSMN1; SMN2KDM4ECYP1A2CYP2D6 | |
| SCHEMBL7820610 | 0.83 | CYP1A2 (0.50) | TDP1MAPTSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL7833002 | 0.74 | TRPV1 (0.44) | TDP1MAPTSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL7833268 | 0.72 | HDAC1 (0.51) | — | |
| SCHEMBL31146864 | 0.71 | TSHR (0.53) | MAPTSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL28675256 | 0.71 | TSHR (0.53) | MAPTSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL28965419 | 0.71 | TSHR (0.53) | MAPTSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL28692968 | 0.71 | TSHR (0.53) | MAPTSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL7057071 | 0.69 | NCEH1 (0.50) | MAPTKDM4EATMNCEH1ALDH1A1 | |
| SCHEMBL5997308 | 0.69 | CYP1A2 (0.53) | TDP1SMN1; SMN2KDM4ECYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737671-B1 | Aromatic hydroxamic acid compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-12-12 | — | — | EP | disclosed |