SCHEMBL7821088

SCHEMBL7821088

COc1nsnc1C1CN2CCC1C2

nearest known ligand 0.67

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 8/20 0.54
CHRM1 P11229 6/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxalic Acid SCHEMBL7826550 0.92 CHRM2 (0.51) CHRM2CHRM1
SCHEMBL7810366 0.91 CHRM2 (0.56) CHRM2CHRM1
Oxalic Acid SCHEMBL7818727 0.85 CHRM2 (0.53) CHRM2CHRM1
SCHEMBL7810892 0.77 CHRM1 (0.57) CHRM2CHRM1
SCHEMBL7819457 0.77 CHRM2 (0.59) CHRM2CHRM1
SCHEMBL8187794 0.76 CHRM2 (0.46) CHRM2CHRM1
SCHEMBL7810667 0.76 CHRM2 (0.61) CHRM2CHRM1
SCHEMBL5932047 0.75 CHRM1 (0.66) CHRM2CHRM1
SCHEMBL7819510 0.75 CHRM1 (0.55) CHRM2CHRM1
SCHEMBL7817946 0.75 CHRM2 (0.60) CHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6265419-B1 IRRITABLE BOWEL DISORDER NOVO NORDISK A/S (DK) 2001-07-24 US claimed
EP-0714394-B1 ANTIPSYCHOTIC METHOD WITH THIADIAZOLE AND OXADIAZOLE DERIVATIVES NOVO NORDISK AS (DK) 2001-06-20 EP claimed
US-5663182-A ADMINISTERING AN AZABICYCLIC RING SUBSTITUTED THIADIAZOLE OR OXADIAZOLE TO A MAMMAL BYMASTER FRANKLIN PORTER (US) 1997-09-02 US claimed
EP-0714394-A1 ANTIPSYCHOTIC METHOD NOVO NORDISK A/S (DK) 1996-06-05 EP claimed
WO-1996014316-A1 A METHOD OF TREATING URINARY BLADDER DYSFUNCTIONS NOVO NORDISK A/S (DK) 1996-05-17 WO claimed
WO-1995005379-A1 ANTIPSYCHOTIC METHOD NOVO NORDISK A/S (DK) 1995-02-23 WO claimed
EP-0544779-A1 HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 1993-06-09 EP claimed
WO-1992003433-A1 HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 1992-03-05 WO claimed
EP-0709093-B1 Method for treating anxiety using an azabicyclic oxadiazole or thiadiazole compound LILLY CO ELI (US) 2000-04-05 EP disclosed
WO-1996013166-A1 METHOD FOR TREATING ANXIETY ELI LILLY AND COMPANY (US) 1996-05-09 WO disclosed
EP-0709093-A2 Method for treating anxiety using an azabicyclic oxadiazole or thiadiazole compound ELI LILLY AND COMPANY (US) 1996-05-01 EP disclosed
US-5484794-A THIA- OR OXA-DIAZOLE COMPOUNDS ELI LILLY AND COMPANY (US) 1996-01-16 US disclosed