⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2032709 | 1.00 | — | — | |
| Boric Acid SCHEMBL27935966 | 0.88 | TSHR (0.30) | — | |
| SCHEMBL8760777 | 0.84 | — | — | |
| SCHEMBL1148058 | 0.84 | — | — | |
| SCHEMBL23054517 | 0.82 | — | — | |
| SCHEMBL13811907 | 0.82 | — | — | |
| SCHEMBL10127534 | 0.82 | — | — | |
| SCHEMBL2618664 | 0.82 | — | — | |
| SCHEMBL5621935 | 0.82 | — | — | |
| SCHEMBL9541878 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3171421-B1 | ORGANIC LIGHT-EMITTING ELEMENT | UNIV KYUSHU NAT UNIV CORP (JP) | 2023-01-25 | — | — | EP | disclosed |
| CN-114085163-A | Method for synthesizing 2,3,3, 3-tetrafluoro-2- (trifluoromethyl) propionitrile by gas-phase catalytic fluorination | 化学与精细化工广东省实验室 | 2022-02-25 | — | — | CN | disclosed |
| US-11254688-B2 | Benzyl-, (pyridin-3-yl)methyl -or (pyridin-4-yl)-methyl-substituted oxadiazolopyridine derivatives as ghrelin O-acyl transferase (GOAT) inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2022-02-22 | — | — | US | disclosed |
| US-20210053985-A1 | BENZYL-, (PYRIDIN-3-YL)METHYL -OR (PYRIDIN-4-YL)-METHYL-SUBSTIITUTED OXADIAZOLOPYRIDINE DERIVATIVES AS GHRELIN O-ACYL TRANSFERASE (GOAT) INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-02-25 | — | — | US | disclosed |
| WO-2021012049-A1 | SUBSTITUTED 2-MORPHOLINOPYRIDINE DERIVATIVES AS ATR KINASE INHIBITORS | REPARE THERAPEUTICS INC. (CA) | 2021-01-28 | — | — | WO | disclosed |
| EP-3266468-B1 | EYEDROPS | NOF CORP (JP) | 2020-10-14 | — | — | EP | disclosed |
| US-20190173020-A1 | COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES | Kyulux North America, Inc. | 2019-06-06 | — | — | US | disclosed |
| US-20180110223-A1 | PHENOXY- OR PYRIDIN-2-YLOXY-AMINOTRIAZINE COMPOUNDS AND THEIR USE AS HERBICIDES | BASF SE (DE) | 2018-04-26 | — | — | US | disclosed |
| US-20180105531-A1 | METHODS AND COMPOSITIONS FOR INHIBITING THE INTERACTION OF MENIN WITH MLL PROTEINS | WELLSPRING BIOSCIENCES LLC | 2018-04-19 | — | — | US | disclosed |
| US-20170213974-A1 | ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND | KYULUX, INC. (JP) | 2017-07-27 | — | — | US | disclosed |
| EP-1090005-A1 | PYRAZOLO 1,5-a]TRIAZINE CORTICOTROPIN RELEASING FACTOR ANTAGONISTS | Du Pont Pharmaceuticals Company (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999067247-A1 | PYRAZOLO[1,5-a]TRIAZINE CORTICOTROPIN RELEASING FACTOR ANTAGONISTS | DU PONT PHARMACEUTICALS COMPANY (US) | 1999-12-29 | — | — | WO | disclosed |
| US-5972841-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1999-10-26 | — | — | US | disclosed |
| US-5665716-A | 24-homo vitamin D derivatives, process for their production and pharmaceutical preparations obtained therefrom | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-09-09 | — | — | US | disclosed |
| EP-0421561-B1 | 24-D-homo-vitamin D-derivatives, a process for their production, pharmaceutical compositions containing them and their use as medicines | SCHERING AG (DE) | 1994-04-06 | — | — | EP | disclosed |
| US-5154755-A | Uracil derivatives and herbicides containing the same as active ingredient | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-10-13 | — | — | US | disclosed |
| EP-0421561-A2 | 24-D-homo-vitamin D-derivatives, a process for their production, pharmaceutical compositions containing them and their use as medicines | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-04-10 | — | — | EP | disclosed |
| EP-0208921-A2 | Hydroformylation of olefinic compounds in the presence of soluble cobalt salt catalysts and an organic nitrile promoter | HENKEL CORPORATION (a Delaware corp.) (US) | 1987-01-21 | — | — | EP | disclosed |
| US-4612403-A | Hydroformylation of olefinic compounds in the presence of a cobalt catalyst and an organic nitrile promoter | HENKEL CORPORATION (US) | 1986-09-16 | — | — | US | disclosed |
| US-4219684-A | REACTION OF AN OLEFIN WITH CARBON MONOXIDE AND HYDROGEN | UOP INC. (US) | 1980-08-26 | — | — | US | disclosed |