Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 20/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7823610 | 0.97 | MAPK14 (0.69) | MAPK14 | |
| SCHEMBL4829462 | 0.88 | MAPK14 (0.81) | MAPK14 | |
| SCHEMBL7813025 | 0.85 | MAPK14 (0.54) | MAPK14 | |
| SCHEMBL4829575 | 0.84 | MAPK14 (0.86) | MAPK14 | |
| SCHEMBL4827243 | 0.82 | MAPK14 (0.65) | MAPK14 | |
| SCHEMBL4829631 | 0.78 | MAPK14 (0.74) | MAPK14 | |
| SCHEMBL4827748 | 0.78 | MAPK14 (0.69) | MAPK14 | |
| SCHEMBL4881154 | 0.77 | MAPK14 (0.71) | MAPK14 | |
| SCHEMBL1140455 | 0.77 | MAPK14 (0.93) | MAPK14 | |
| SCHEMBL4824608 | 0.76 | MAPK14 (0.87) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1163237-A1 | AMIDE DERIVATIVES | AstraZeneca AB (SE) | 2001-12-19 | — | — | EP | disclosed |
| WO-2000055153-A1 | AMIDE DERIVATIVES | ASTRAZENECA AB (SE) | 2000-09-21 | — | — | WO | disclosed |