Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C8 | P10632 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | SRD5A2 | P31213 | 7/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CDC25B | P30305 | 2/20 | 0.55 |
| ▸ | CDC25A | P30304 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyromellitic Acid SCHEMBL9614897 | 0.90 | TSHR (0.71) | CYP2C8CYP2C9KDM4ESRD5A2TDP1 | |
| SCHEMBL29921802 | 0.86 | KDM4E (0.85) | CYP2C8CYP2C9KDM4ESRD5A2TDP1 | |
| SCHEMBL598423 | 0.86 | KDM4E (0.85) | CYP2C8CYP2C9KDM4ESRD5A2TDP1 | |
| SCHEMBL6014019 | 0.86 | AKR1C3 (0.71) | CYP2C8CYP2C9KDM4ESRD5A2TDP1 | |
| SCHEMBL6056968 | 0.86 | AKR1C3 (0.71) | CYP2C8CYP2C9KDM4ESRD5A2TDP1 | |
| SCHEMBL15793780 | 0.86 | AKR1C3 (0.71) | CYP2C8CYP2C9KDM4ESRD5A2TDP1 | |
| SCHEMBL30549431 | 0.86 | AKR1C3 (0.71) | CYP2C8CYP2C9KDM4ESRD5A2TDP1 | |
| SCHEMBL4294255 | 0.85 | NR4A1 (0.69) | CYP2C8CYP2C9KDM4ESRD5A2TDP1 | |
| SCHEMBL6056928 | 0.85 | AKR1C3 (0.69) | CYP2C8CYP2C9KDM4ESRD5A2TDP1 | |
| SCHEMBL6057027 | 0.85 | AKR1C3 (0.69) | CYP2C8CYP2C9KDM4ESRD5A2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |