Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 7/20 | 0.39 |
| ▸ | ACHE | P22303 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7835397 | 0.83 | EGFR (0.43) | EGFRBCHEACHEKDM4ECHRM2 | |
| SCHEMBL7832227 | 0.83 | EGFR (0.43) | EGFRBCHEACHEKDM4ECHRM2 | |
| SCHEMBL14079299 | 0.83 | EGFR (0.48) | EGFRBCHEACHEKDM4ECHRM2 | |
| SCHEMBL14423952 | 0.82 | EGFR (0.47) | EGFRKDM4ECHRM2CHRM1DRD2 | |
| SCHEMBL3170951 | 0.82 | EGFR (0.47) | EGFRBCHEACHEKDM4ECHRM2 | |
| SCHEMBL7835249 | 0.81 | EGFR (0.45) | EGFRBCHEACHEKDM4ECHRM2 | |
| SCHEMBL7823369 | 0.79 | EGFR (0.44) | EGFRBCHEACHEKDM4ECHRM2 | |
| SCHEMBL12245270 | 0.79 | EGFR (0.45) | EGFRKDM4ECHRM2CHRM1DRD2 | |
| SCHEMBL3167025 | 0.74 | EGFR (0.57) | EGFRKDM4EKMT2ASMN1; SMN2GAA | |
| SCHEMBL13525404 | 0.74 | EGFR (0.83) | EGFRKDM4EKMT2ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0681570-B1 | PROCESS FOR PREPARING QUINOLINE AMINES | MINNESOTA MINING & MFG (US) | 2001-03-14 | — | — | EP | claimed |
| US-5395937-A | Process for preparing quinoline amines | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-03-07 | — | — | US | claimed |