SCHEMBL7823175

SCHEMBL7823175

CCCCCCOc1nsnc1C1CN2CCCC1C2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 4/20 0.58
CHRM1 P11229 3/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7810995 0.99 CHRM2 (0.59) CHRM2CHRM1
SCHEMBL7817946 0.95 CHRM2 (0.60) CHRM2CHRM1
Oxalic Acid SCHEMBL7821063 0.95 CHRM2 (0.56) CHRM2CHRM1
Oxalic Acid SCHEMBL7810891 0.94 CHRM2 (0.56) CHRM2CHRM1
SCHEMBL7819457 0.91 CHRM2 (0.59) CHRM2CHRM1
Oxalic Acid SCHEMBL7818466 0.90 CHRM2 (0.57) CHRM2CHRM1
SCHEMBL7811176 0.87 CHRM1 (0.67) CHRM2CHRM1
SCHEMBL7811603 0.86 CHRM2 (0.58) CHRM2CHRM1
SCHEMBL7818970 0.86 CHRM1 (0.67) CHRM2CHRM1
SCHEMBL7810667 0.86 CHRM2 (0.61) CHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6271229-B1 ADMINISTERING A 1,2,5-OXADIAZOLE COMPOUND OR 1,2,5-THIADIAZOLE COMPOUND NOVO NORDISK A/S (DK) 2001-08-07 US claimed
EP-0714394-B1 ANTIPSYCHOTIC METHOD WITH THIADIAZOLE AND OXADIAZOLE DERIVATIVES NOVO NORDISK AS (DK) 2001-06-20 EP claimed
US-5574043-A ALZHEIMERS, GLAUCOMA, ANALGESIC NOVO NORDISK A/S (DK) 1996-11-12 US claimed
EP-0714394-A1 ANTIPSYCHOTIC METHOD NOVO NORDISK A/S (DK) 1996-06-05 EP claimed
WO-1996014316-A1 A METHOD OF TREATING URINARY BLADDER DYSFUNCTIONS NOVO NORDISK A/S (DK) 1996-05-17 WO claimed
WO-1995005379-A1 ANTIPSYCHOTIC METHOD NOVO NORDISK A/S (DK) 1995-02-23 WO claimed
WO-1996013166-A1 METHOD FOR TREATING ANXIETY ELI LILLY AND COMPANY (US) 1996-05-09 WO disclosed
US-5484794-A THIA- OR OXA-DIAZOLE COMPOUNDS ELI LILLY AND COMPANY (US) 1996-01-16 US disclosed