Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7828782 | 1.00 | KMT2A (1.00) | KMT2APOLBCYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL728227 | 0.92 | POLB (0.88) | KMT2APOLBCYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL7823312 | 0.86 | POLB (1.00) | KMT2APOLBCYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL15075817 | 0.86 | POLB (0.77) | KMT2APOLBCYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL15075815 | 0.86 | POLB (0.77) | KMT2APOLBCYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL7821921 | 0.86 | POLB (0.77) | KMT2APOLBCYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL7822144 | 0.85 | POLB (1.00) | KMT2APOLBCYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL28747379 | 0.84 | KMT2A (0.70) | KMT2APOLBCYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL657374 | 0.84 | KMT2A (0.72) | KMT2APOLBCYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL7824145 | 0.82 | CYP2C9 (1.00) | KMT2APOLBCYP2C9CYP2C19L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |