Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | DHODH | Q02127 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3924670 | 0.79 | DHODH (0.63) | NPSR1DHODHPKMPARP1PARP15 | |
| SCHEMBL10527844 | 0.78 | HSD17B10 (0.54) | MAPTPOLBPKMTSHRHSD17B10 | |
| SCHEMBL3914856 | 0.77 | DHODH (0.69) | NPSR1DHODHMAPTPOLBHSD17B10 | |
| SCHEMBL925741 | 0.76 | SMN1; SMN2 (0.57) | MAPTPOLBPKMTSHRHSD17B10 | |
| SCHEMBL30621955 | 0.76 | SMN1; SMN2 (0.57) | MAPTPOLBPKMTSHRHSD17B10 | |
| SCHEMBL6346820 | 0.76 | KMT2A (0.65) | MAPTPOLBPKMKDM4E | |
| SCHEMBL3926481 | 0.75 | PARP1 (0.77) | NPSR1DHODHPOLBPKMPARP1 | |
| SCHEMBL8762690 | 0.75 | DHODH (0.76) | NPSR1DHODHPOLBPARP1PARP15 | |
| SCHEMBL10841541 | 0.73 | NPSR1 (0.57) | NPSR1DHODHMAPTPARP1PARP15 | |
| SCHEMBL3990108 | 0.72 | DHODH (0.73) | DHODHPOLBPARP1PARP15PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |