Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 20/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8479219 | 1.00 | TACR1 (0.63) | TACR1 | |
| SCHEMBL7815972 | 0.94 | TACR1 (0.66) | TACR1 | |
| SCHEMBL7831297 | 0.93 | TACR1 (0.64) | TACR1 | |
| SCHEMBL8475971 | 0.93 | TACR1 (0.64) | TACR1 | |
| SCHEMBL7831307 | 0.92 | TACR1 (0.62) | TACR1 | |
| SCHEMBL8480292 | 0.92 | TACR1 (0.67) | TACR1 | |
| SCHEMBL7816140 | 0.92 | TACR1 (0.67) | TACR1 | |
| Hydrochloric Acid SCHEMBL7826469 | 0.92 | TACR1 (0.61) | TACR1 | |
| SCHEMBL8481306 | 0.90 | TACR1 (0.62) | TACR1 | |
| SCHEMBL7825096 | 0.90 | TACR1 (0.62) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0655442-B1 | Piperazine derivatives as Tachykinin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-05-23 | — | — | EP | disclosed |
| EP-0655442-A1 | Piperazine derivatives as Tachykinin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-05-31 | — | — | EP | disclosed |