Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 19/20 | 0.75 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7813828 | 0.92 | CCR3 (0.64) | CCR3MAPTHTR2A | |
| SCHEMBL7813749 | 0.90 | CCR3 (0.67) | CCR3MAPT | |
| SCHEMBL5348555 | 0.86 | CCR3 (0.56) | CCR3MAPTHTR2A | |
| SCHEMBL7820813 | 0.86 | CCR3 (0.56) | CCR3MAPTHTR2A | |
| SCHEMBL7829024 | 0.85 | CCR3 (0.55) | CCR3MAPTHTR2A | |
| SCHEMBL7823114 | 0.85 | CCR3 (0.74) | CCR3MAPTHTR2A | |
| SCHEMBL7822009 | 0.84 | CCR3 (0.75) | CCR3MAPT | |
| SCHEMBL7829373 | 0.84 | CCR3 (0.77) | CCR3 | |
| SCHEMBL7824203 | 0.83 | CCR3 (0.75) | CCR3 | |
| SCHEMBL7821497 | 0.82 | CCR3 (0.57) | CCR3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140834-A1 | HETEROCYCLIC PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Du Pont Pharmaceuticals Company (US) | 2001-10-10 | — | — | EP | claimed |
| WO-2000035877-A1 | HETEROCYCLIC PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-06-22 | — | — | WO | claimed |
| EP-1140834-A1 | HETEROCYCLIC PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Du Pont Pharmaceuticals Company (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035877-A1 | HETEROCYCLIC PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-06-22 | — | — | WO | disclosed |