Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR2 | O43603 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6161429 | 0.99 | GALR2 (0.34) | GALR2P2RX7HTTKDM4EALDH1A1 | |
| SCHEMBL6991378 | 0.92 | AXL (0.35) | GALR2P2RX7HTTKDM4EALDH1A1 | |
| SCHEMBL7831053 | 0.92 | MAP4K1 (0.36) | — | |
| SCHEMBL6997579 | 0.92 | AXL (0.35) | GALR2P2RX7HTTKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6991842 | 0.91 | AXL (0.34) | GALR2P2RX7HTTKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6991405 | 0.91 | AXL (0.34) | GALR2P2RX7HTTKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6993609 | 0.91 | AXL (0.34) | GALR2P2RX7HTTKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6158110 | 0.91 | MAP4K1 (0.35) | — | |
| Hydrochloric Acid SCHEMBL6158437 | 0.91 | GALR2 (0.34) | GALR2P2RX7HTTKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6158464 | 0.91 | POLB (0.37) | P2RX7ALDH1A1HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131312-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION, LTD. (KR) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000029403-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2000-05-25 | — | — | WO | disclosed |