Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 2/20 | 1.00 |
| ▸ | CA9 | Q16790 | 11/20 | 0.65 |
| ▸ | CA12 | O43570 | 9/20 | 0.65 |
| ▸ | CA1 | P00915 | 6/20 | 0.65 |
| ▸ | CA7 | P43166 | 3/20 | 0.65 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | GAA | P10253 | 5/20 | 0.60 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | CASP1 | P29466 | 4/20 | 0.60 |
| ▸ | CASP7 | P55210 | 4/20 | 0.60 |
| ▸ | GLA | P06280 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Demethylsuberosin SCHEMBL4773171 | 0.82 | CA9 (0.78) | SRD5A1CA9CA12CA1CA7 | |
| SCHEMBL15171953 | 0.81 | CA9 (0.68) | SRD5A1CA9CA12CA1CA7 | |
| SCHEMBL27970804 | 0.81 | CA9 (0.68) | SRD5A1CA9CA12CA1CA7 | |
| SCHEMBL10205474 | 0.80 | SRD5A1 (0.66) | SRD5A1CA9CA12CA1CA7 | |
| SCHEMBL30722445 | 0.78 | SRD5A1 (0.64) | SRD5A1CA9CA12CA1CA7 | |
| SCHEMBL4882410 | 0.78 | CA9 (0.71) | SRD5A1CA9CA12CA1CA7 | |
| SCHEMBL4882406 | 0.78 | CA9 (0.71) | SRD5A1CA9CA12CA1CA7 | |
| SCHEMBL7822382 | 0.78 | SRD5A1 (0.63) | SRD5A1CA9CA12CA1CA7 | |
| SCHEMBL19774161 | 0.77 | SRD5A1 (0.62) | SRD5A1CA9CA12CA1CA7 | |
| SCHEMBL7853319 | 0.77 | SRD5A1 (0.62) | SRD5A1CA9CA12CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116574108-A | Synthesis method of psoralen | 河南中烟工业有限责任公司 | 2023-08-11 | — | — | CN | claimed |
| CN-111072605-B | Preparation method of fluoroalkyl-substituted benzofuran derivative or indole derivative | 赣南医学院 | 2021-11-02 | — | — | CN | claimed |
| EP-1133498-A2 | AMINO-AND MERCURIO-SUBSTITUTED 4', 5'-DIHYDROPSORALENS AND THERAPEUTICAL USES THEREOF | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 2001-09-19 | — | — | EP | claimed |
| US-6255324-B1 | MICROBIOCIDES; SKIN DISORDERS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2001-07-03 | — | — | US | claimed |
| WO-2000031081-A2 | AMINO- AND MERCURIO-SUBSTITUTED 4',5'-DIHYDROPSORALENS AND THERAPEUTICAL USES THEREOF | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 2000-06-02 | — | — | WO | claimed |
| US-5179217-A | Skin disorders | BACCICHETTI FRANCAROSA (IT) | 1993-01-12 | — | — | US | claimed |
| CN-116574108-A | Synthesis method of psoralen | 河南中烟工业有限责任公司 | 2023-08-11 | — | — | CN | disclosed |
| CN-116574108-A | Synthesis method of psoralen | 河南中烟工业有限责任公司 | 2023-08-11 | — | — | CN | disclosed |
| CN-111072605-B | Preparation method of fluoroalkyl-substituted benzofuran derivative or indole derivative | 赣南医学院 | 2021-11-02 | — | — | CN | disclosed |
| CN-111072605-A | Preparation method of fluoroalkyl-substituted benzofuran derivative or indole derivative | 赣南医学院 | 2020-04-28 | — | — | CN | disclosed |
| EP-1133498-A2 | AMINO-AND MERCURIO-SUBSTITUTED 4', 5'-DIHYDROPSORALENS AND THERAPEUTICAL USES THEREOF | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 2001-09-19 | — | — | EP | disclosed |
| US-6255324-B1 | MICROBIOCIDES; SKIN DISORDERS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2001-07-03 | — | — | US | disclosed |
| WO-2000031081-A2 | AMINO- AND MERCURIO-SUBSTITUTED 4',5'-DIHYDROPSORALENS AND THERAPEUTICAL USES THEREOF | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 2000-06-02 | — | — | WO | disclosed |
| US-5179217-A | Skin disorders | BACCICHETTI FRANCAROSA (IT) | 1993-01-12 | — | — | US | disclosed |
| US-5001147-A | Photochemotherapic method of treating psoriasis by using methylangelicin compounds | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 1991-03-19 | — | — | US | disclosed |