Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 17/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 17/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 10/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 8/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8136776 | 0.92 | CYP3A4 (0.53) | CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2 | |
| SCHEMBL7505182 | 0.91 | CYP3A4 (0.47) | CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2 | |
| SCHEMBL1812877 | 0.89 | CYP3A4 (0.60) | CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2 | |
| SCHEMBL8892144 | 0.87 | CYP3A4 (0.48) | CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2 | |
| SCHEMBL1816224 | 0.87 | CYP3A4 (0.48) | CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2 | |
| SCHEMBL7839635 | 0.86 | CYP1A2 (0.49) | CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2 | |
| SCHEMBL4969583 | 0.86 | CYP3A4 (0.57) | CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2 | |
| SCHEMBL7499692 | 0.85 | CYP3A4 (0.48) | CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2 | |
| SCHEMBL8804870 | 0.82 | CYP3A4 (0.51) | CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2 | |
| SCHEMBL8806511 | 0.80 | CYP2C9 (0.48) | CYP3A4CYP2C9CYP2D6CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723544-B1 | ALKOXY ALKYL CARBAMATES OF IMIDAZO[1,2-a]PYRIDINES | BYK GULDEN LOMBERG CHEM FAB (DE) | 2001-04-18 | — | — | EP | disclosed |
| US-5719161-A | REACTING AN IMIDAZO(1,2-A)PYRIDINE WITH A PHENYLCARBAMATE; USEFUL IN THE TREATMENT OF GASTROINTESTINAL DISEASES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1998-02-17 | — | — | US | disclosed |
| EP-0723544-A1 | ALKOXY ALKYL CARBAMATES FROM IMIDAZO (1,2-a)PYRIDINES | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1996-07-31 | — | — | EP | disclosed |
| WO-1995010518-A1 | ALKOXY ALKYL CARBAMATES FROM IMIDAZO (1,2-a)PYRIDINES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1995-04-20 | — | — | WO | disclosed |