Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 9/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7833056 | 1.00 | TACR1 (0.51) | TACR1HTR6CA1CA2CA4 | |
| SCHEMBL7828087 | 1.00 | TACR1 (0.51) | TACR1HTR6CA1CA2CA4 | |
| SCHEMBL7817009 | 0.88 | KMT2A (0.45) | TACR1MEN1KMT2ADRD2DRD3 | |
| SCHEMBL7817012 | 0.88 | KMT2A (0.45) | TACR1MEN1KMT2ADRD2DRD3 | |
| SCHEMBL7051258 | 0.85 | TACR1 (0.45) | TACR1CA1CA2MEN1KMT2A | |
| SCHEMBL27365754 | 0.83 | TACR1 (0.53) | TACR1MEN1KMT2A | |
| SCHEMBL7817895 | 0.82 | TACR1 (0.44) | TACR1KMT2APOLBDRD2DRD3 | |
| Hydrochloric Acid SCHEMBL7837990 | 0.82 | TACR1 (0.52) | TACR1MEN1KMT2A | |
| SCHEMBL9374751 | 0.82 | TACR1 (0.49) | TACR1 | |
| SCHEMBL9210577 | 0.82 | TACR1 (0.49) | TACR1MEN1KMT2APOLBDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0655996-B1 | SUBSTITUTED BENZYLAMINO NITROGEN CONTAINING NON-AROMATIC HETEROCYCLES | PFIZER (US) | 2001-11-07 | — | — | EP | claimed |
| EP-1114823-A2 | Substituted benzylamino nitrogen containing non-aromatic heterocycles | PFIZER INC. (US) | 2001-07-11 | — | — | EP | claimed |