Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | CTSD | P07339 | 1/20 | 0.53 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.47 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31167606 | 0.84 | ABCG2 (0.77) | ABCG2MAOBCTSDGPR52ABCB1 | |
| SCHEMBL31561740 | 0.82 | ABCG2 (0.64) | ABCG2MAOBCTSDGPR52ABCB1 | |
| SCHEMBL1697561 | 0.82 | ABCG2 (0.64) | ABCG2MAOBCTSDGPR52ABCB1 | |
| SCHEMBL29954715 | 0.82 | ABCG2 (0.64) | ABCG2MAOBCTSDGPR52ABCB1 | |
| SCHEMBL9178467 | 0.82 | ABCG2 (0.64) | ABCG2MAOBCTSDGPR52ABCB1 | |
| SCHEMBL7469828 | 0.82 | ABCG2 (0.64) | ABCG2MAOBCTSDGPR52ABCB1 | |
| SCHEMBL15821571 | 0.81 | ABCG2 (0.62) | ABCG2MAOBCTSDGPR52ABCB1 | |
| Water SCHEMBL3048073 | 0.81 | ABCG2 (0.62) | ABCG2MAOBCTSDGPR52ABCB1 | |
| SCHEMBL15563363 | 0.80 | CA12 (0.69) | ABCG2MAOBCTSDGPR52ABCB1 | |
| SCHEMBL15563364 | 0.80 | CA12 (0.69) | ABCG2MAOBCTSDGPR52ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686636-B1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA CO (JP) | 2001-04-04 | — | — | EP | disclosed |
| US-5840895-A | INTERMEDIATES FOR ANTIALLERGENS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1998-11-24 | — | — | US | disclosed |
| US-5686442-A | ANTIALLERGENS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-11-11 | — | — | US | disclosed |
| EP-0686636-A1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-12-13 | — | — | EP | disclosed |