Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 6/20 | 0.59 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | TYMP | P19971 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3090285 | 0.86 | CYP1A2 (0.59) | CYP1A2CYP2A6ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL599157 | 0.84 | CYP1A2 (0.62) | CYP1A2CYP2A6ALDH1A1DAOTAAR1 | |
| SCHEMBL14496815 | 0.82 | CYP1A2 (0.59) | CYP1A2CYP2A6ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL10900222 | 0.77 | CYP1A2 (0.59) | CYP1A2CYP2A6ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL15345377 | 0.77 | CYP1A2 (0.59) | CYP1A2CYP2A6ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL424167 | 0.77 | CYP1A2 (1.00) | CYP1A2CYP2A6ALDH1A1CYP3A4HPGD | |
| SCHEMBL29463284 | 0.77 | CYP1A2 (1.00) | CYP1A2CYP2A6ALDH1A1CYP3A4HPGD | |
| SCHEMBL395673 | 0.76 | ESR1 (0.44) | CYP1A2CYP2A6ALDH1A1TAAR1HSD17B10 | |
| SCHEMBL392411 | 0.75 | — | — | |
| SCHEMBL5235003 | 0.75 | CYP1A2 (0.50) | CYP1A2CYP2A6ALDH1A1HPGDPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454501-B1 | Benzylidenethiazolidine derivatives, their preparation and their use for the inhibition of lipid peroxides | SANKYO CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| EP-0839812-A1 | Preparation of benzylthiazolidine derivatives | Sankyo Company Limited (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5387596-A | Treating arteriosclerosis | SANKYO COMPANY, LIMITED (JP) | 1995-02-07 | — | — | US | disclosed |
| EP-0454501-A2 | Benzylidenethiazolidine derivatives, their preparation and their use for the inhibition of lipid peroxides | Sankyo Company Limited (JP) | 1991-10-30 | — | — | EP | disclosed |