Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29618948 | 0.93 | KMT2A (0.53) | KMT2AEPHX2NR1H4MRGPRX4OPRD1 | |
| SCHEMBL29679265 | 0.93 | KMT2A (0.53) | KMT2AEPHX2NR1H4MRGPRX4OPRD1 | |
| SCHEMBL119110 | 0.93 | KMT2A (0.53) | KMT2AEPHX2NR1H4MRGPRX4OPRD1 | |
| Benzoic Acid SCHEMBL27028192 | 0.85 | KMT2A (0.56) | KMT2AEPHX2OPRD1 | |
| SCHEMBL5551698 | 0.84 | KMT2A (0.49) | KMT2AEPHX2OPRD1NPC1RAB9A | |
| SCHEMBL22498215 | 0.84 | KMT2A (0.55) | KMT2AEPHX2OPRD1 | |
| SCHEMBL14452747 | 0.83 | EPHX2 (0.48) | KMT2AEPHX2OPRD1 | |
| SCHEMBL3064762 | 0.82 | EPHX2 (0.49) | KMT2AEPHX2ROCK2ROCK1 | |
| SCHEMBL1855344 | 0.81 | EPHX2 (0.53) | KMT2AEPHX2NR1H4 | |
| SCHEMBL3177417 | 0.81 | KMT2A (0.62) | KMT2AEPHX2OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |