Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 8/20 | 0.80 |
| ▸ | CA9 | Q16790 | 8/20 | 0.80 |
| ▸ | CA1 | P00915 | 6/20 | 0.80 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL458085 | 0.89 | CA12 (1.00) | CA12CA9CA1DDAH1ALDH1A1 | |
| SCHEMBL68336 | 0.78 | TSHR (0.67) | CA12CA9CA1ALDH1A1HSD17B10 | |
| SCHEMBL9132210 | 0.75 | TSHR (0.63) | CA12CA9CA1ALDH1A1HSD17B10 | |
| SCHEMBL9134050 | 0.75 | TSHR (0.63) | CA12CA9CA1ALDH1A1HSD17B10 | |
| SCHEMBL9132448 | 0.75 | TSHR (0.63) | CA12CA9CA1ALDH1A1HSD17B10 | |
| SCHEMBL9130714 | 0.75 | TSHR (0.63) | CA12CA9CA1ALDH1A1HSD17B10 | |
| SCHEMBL9134460 | 0.75 | TSHR (0.63) | CA12CA9CA1ALDH1A1HSD17B10 | |
| SCHEMBL9133947 | 0.75 | TSHR (0.63) | CA12CA9CA1ALDH1A1HSD17B10 | |
| SCHEMBL9134279 | 0.75 | TSHR (0.63) | CA12CA9CA1ALDH1A1HSD17B10 | |
| SCHEMBL9136978 | 0.75 | TSHR (0.63) | CA12CA9CA1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |