Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.53 |
| ▸ | FAAH | O00519 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.50 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TOP2A | P11388 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3062222 | 0.91 | MEN1 (0.64) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL541010 | 0.87 | POLB (0.57) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL7833275 | 0.84 | APEX1 (0.57) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL11431402 | 0.83 | POLB (0.52) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL540967 | 0.83 | APEX1 (0.58) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL15081856 | 0.81 | MAPK1 (0.54) | MEN1KMT2APOLBMAPTL3MBTL1 | |
| SCHEMBL15064152 | 0.81 | MAPK1 (0.54) | MEN1KMT2APOLBMAPTL3MBTL1 | |
| SCHEMBL15081854 | 0.81 | MAPK1 (0.54) | MEN1KMT2APOLBMAPTL3MBTL1 | |
| SCHEMBL12575336 | 0.80 | CETP (0.53) | POLBMAPTNTRK1NTRK2LMNA | |
| SCHEMBL11020420 | 0.80 | CETP (0.53) | POLBMAPTNTRK1NTRK2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737671-B1 | Aromatic hydroxamic acid compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-12-12 | — | — | EP | disclosed |
| US-5804601-A | USEFUL FOR TREATING ALZHEIMER'S DISEASE, MULTIPLE SCLEROSIS, BACTERIAL OR VIRAL MENINGITIS, DOWN'S SYNDROME AND PARKINSON'S DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-08 | — | — | US | disclosed |
| EP-0737671-A2 | Aromatic hydroxamic acid compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1996-10-16 | — | — | EP | disclosed |