Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 19/20 | 0.73 |
| ▸ | HTR2A | P28223 | 2/20 | 0.65 |
| ▸ | CCR2 | P41597 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7825964 | 0.96 | CCR3 (0.75) | CCR3HTR2ACCR2 | |
| SCHEMBL5350885 | 0.91 | CCR3 (0.69) | CCR3HTR2ACCR2 | |
| SCHEMBL5348263 | 0.89 | CCR3 (0.69) | CCR3HTR2ACCR2 | |
| SCHEMBL6841243 | 0.88 | CCR3 (0.76) | CCR3HTR2A | |
| SCHEMBL5353823 | 0.88 | CCR3 (0.76) | CCR3HTR2A | |
| Hydrochloric Acid SCHEMBL5364218 | 0.88 | CCR3 (0.76) | CCR3HTR2A | |
| SCHEMBL7829378 | 0.88 | CCR3 (0.75) | CCR3HTR2A | |
| SCHEMBL5346262 | 0.86 | CCR3 (0.70) | CCR3HTR2ACCR2 | |
| SCHEMBL7825001 | 0.86 | CCR3 (0.76) | CCR3 | |
| SCHEMBL5353032 | 0.85 | CCR3 (0.60) | CCR3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140834-A1 | HETEROCYCLIC PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Du Pont Pharmaceuticals Company (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035877-A1 | HETEROCYCLIC PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-06-22 | — | — | WO | disclosed |