Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.47 |
| ▸ | CBFB | Q13951 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | BRS3 | P32247 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.39 |
| ▸ | F9 | P00740 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7830427 | 0.92 | CYP11B1 (0.47) | CYP11B1CYP11B2CBFBMAOAMAOB | |
| SCHEMBL7832544 | 0.92 | CBFB (0.47) | CYP11B1CYP11B2CBFBMAOAMAOB | |
| Hydrochloric Acid SCHEMBL8158760 | 0.91 | CBFB (0.46) | CYP11B1CYP11B2CBFBMAOAMAOB | |
| SCHEMBL7830709 | 0.91 | CBFB (0.50) | CYP11B1CYP11B2CBFBMAOAMAOB | |
| Hydrochloric Acid SCHEMBL7821802 | 0.90 | CBFB (0.49) | CYP11B1CYP11B2CBFBMAOAMAOB | |
| SCHEMBL7831108 | 0.88 | SMN1; SMN2 (0.55) | CYP11B1CYP11B2CBFBMAOAMAOB | |
| Hydrochloric Acid SCHEMBL8142735 | 0.87 | SMN1; SMN2 (0.54) | CYP11B1CYP11B2CBFBMAOAMAOB | |
| SCHEMBL7833677 | 0.85 | CBFB (0.47) | CYP11B1CYP11B2CBFBMAOAMAOB | |
| SCHEMBL7837226 | 0.85 | CBFB (0.46) | CYP11B1CYP11B2CBFBMAOAMAOB | |
| SCHEMBL7832662 | 0.84 | CBFB (0.49) | CYP11B1CYP11B2CBFBMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894795-B1 | Benzimidazole, benzoxazole and benzothiazole derivatives, their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-06-06 | — | — | EP | disclosed |
| US-6040327-A | INHIBITORS OF INTERLEUKINS; TREATING RHEUMATOID ARTHRITIS OR ARTHROSIS | ADIR ET COMPAGNIE (FR) | 2000-03-21 | — | — | US | disclosed |
| EP-0894795-A1 | Benzimidazole, benzoxazole and benzothiazole derivatives, their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-02-03 | — | — | EP | disclosed |